Endocrine Abstracts

Background: The presence of the Y chromosome and Y-specific sequences (e.g: SRY, DYZ1, DYZ3, DYS132, ZFY, and TSPY, etc) in Turner syndrome patients is a risk factor for gonadal tumors (mostly gonadoblastoma) in dysgenetic gonads. Unfortunately approximately 60% of gonadoblastoma cases, there is a potential to progress towards invasive germ cell tumors (mostly dysgerminoma). Girls with Y chromosomal material also present a higher risk of virilization...